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BS patients showed an improvement in BP at 1 year, followed by progressive rise over the consequent years which was thought to be associated to increasing age and weight gain [66, 7]

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The -hydroxyl of carnitine is acylated so that acyl-coenzyme A (acyl-CoA), which cannot directly cross the inner mitochondrial membrane, can be transported into the mitochondrial matrix and then participate in -oxidation to produce ATP

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